| Local Name | Desire 21 Pro 5G |
| Technology | GSM / HSPA / LTE / 5G |
| 4G Bands | 1, 3, 5, 7, 8, 20, 28, 38, 39, 40, 41 |
| 3G Bands | HSDPA 850 / 900 / 1700(AWS) / 1900 / 2100 |
| 2G Bands | GSM 850 / 900 / 1800 / 1900 - SIM 1 & SIM 2 |
| Speed | HSPA, LTE-A |
| Announced | 2021, January 13 |
| Status | Available. Released 2021, January 21 |
| Dimensions | 167.1 x 78.1 x 9.4 mm (6.58 x 3.07 x 0.37 in) |
| Weight | 205 g (7.23 oz) |
| SIM | Hybrid Dual SIM (Nano-SIM, dual stand-by) |
| Display Type | Li-Po 5000 mAh, non-removable |
| Screen Size | 6.7 inches, 108.4 cm2 (~83.0% screen-to-body ratio) |
| Resolution | 1080 x 2400 pixels, 20:9 ratio (~393 ppi density) |
| OS | Android 10 |
| Chipset | Qualcomm SM6350 Snapdragon 690 5G (8 nm) |
| CPU | Octa-core (2x2.0 GHz Kryo 560 Gold & 6x1.7 GHz Kryo 560 Silver) |
| GPU | Adreno 619 |
| Card Slot | microSDXC (uses shared SIM slot) |
| Internal Memory | 128GB 8GB RAM |
| Camera Features | HDR |
| Video | 1080p@30fps |
| Loudspeaker | Yes |
| 3.5mm Jack | No |
| WLAN | Wi-Fi 802.11 a/b/g/n/ac, dual-band, Wi-Fi Direct |
| Bluetooth | 5.1, A2DP, LE |
| NFC | Yes |
| Radio | No |
| USB | USB Type-C 2.0, OTG |
| Sensors | Fingerprint (side-mounted), accelerometer, gyro, proximity, compass |
| Colors | Blue, Purple |