| Local Name | Mate 50E |
| Technology | GSM / CDMA / HSPA / CDMA2000 / LTE |
| 4G Bands | 1, 2, 3, 4, 5, 7, 8, 12, 17, 18, 19, 20, 26, 28, 34, 38, 39, 40, 41 |
| 3G Bands | HSDPA 800 / 850 / 900 / 1700(AWS) / 1900 / 2100 | CDMA2000 1x |
| 2G Bands | GSM 850 / 900 / 1800 / 1900 - SIM 1 & SIM 2 (dual-SIM model only) | CDMA 800 |
| Speed | HSPA, LTE-A |
| Announced | 2022, September 06 |
| Status | Available. Released 2022, October 23 |
| Dimensions | 161.5 x 76.1 x 8 mm (6.36 x 3.00 x 0.31 in) |
| Weight | 201 g (7.09 oz) |
| SIM | Single SIM (Nano-SIM) or Hybrid Dual SIM (Nano-SIM, dual stand-by) |
| Display Type | Li-Po 4460 mAh, non-removable |
| Screen Size | 6.7 inches, 108.9 cm2 (~88.6% screen-to-body ratio) |
| Resolution | 1224 x 2700 pixels (~442 ppi density) |
| OS | HarmonyOS 3.0 |
| Chipset | Qualcomm SM7325 Snapdragon 778G 5G (6 nm) |
| CPU | Octa-core (1x2.4 GHz Cortex-A78 & 3x2.2 GHz Cortex-A78 & 4x1.9 GHz Cortex-A55) |
| GPU | Adreno 642L |
| Card Slot | NM (Nano Memory), up to 256GB (uses shared SIM slot) |
| Internal Memory | 128GB 8GB RAM, 256GB 8GB RAM | UFS 3.1 |
| Camera Features | HDR, panorama |
| Video | 4K@30/60fps, 1080p@30/60fps |
| Loudspeaker | Yes, with stereo speakers |
| 3.5mm Jack | No |
| Sound | 32-bit/384kHz audio |
| WLAN | Wi-Fi 802.11 a/b/g/n/ac/6, dual-band, Wi-Fi Direct |
| Bluetooth | 5.2, A2DP, LE |
| NFC | Yes |
| Infrared Port | Yes |
| Radio | No |
| USB | USB Type-C 3.1, OTG |
| Sensors | Fingerprint (under display, optical), accelerometer, gyro, proximity, barometer, compass, color spectrum |
| Colors | Black, Silver, Purple |
