| Local Name | Galaxy M53 |
| Technology | GSM / HSPA / LTE / 5G |
| 4G Bands | 1, 2, 3, 4, 5, 7, 8, 12, 17, 20, 26, 28, 38, 40, 41, 66 |
| 3G Bands | HSDPA 850 / 900 / 1700(AWS) / 1900 / 2100 |
| 2G Bands | GSM 850 / 900 / 1800 / 1900 - SIM 1 & SIM 2 |
| Speed | HSPA, LTE-A, 5G |
| Announced | 2022, April 07 |
| Status | Available. Released 2022, April 22 |
| Dimensions | 164.7 x 77 x 7.4 mm (6.48 x 3.03 x 0.29 in) |
| Weight | 176 g (6.21 oz) |
| Build | Glass front (Gorilla Glass 5), plastic back, plastic frame |
| SIM | Hybrid Dual SIM (Nano-SIM, dual stand-by) |
| Display Type | Li-Ion 5000 mAh, non-removable |
| Screen Size | 6.7 inches, 108.1 cm2 (~85.3% screen-to-body ratio) |
| Resolution | 1080 x 2408 pixels, 20:9 ratio (~394 ppi density) |
| Protection | Corning Gorilla Glass 5 |
| OS | Android 12, upgradable to Android 13, One UI 5.1 |
| Chipset | Mediatek MT6877 Dimensity 900 (6 nm) |
| CPU | Octa-core (2x2.4 GHz Cortex-A78 & 6x2.0 GHz Cortex-A55) |
| GPU | Mali-G68 MC4 |
| Card Slot | microSDXC (uses shared SIM slot) |
| Internal Memory | 128GB 6GB RAM, 128GB 8GB RAM, 256GB 8GB RAM |
| Camera Features | LED flash, panorama, HDR |
| Video | 4K@30fps, 1080p@30fps |
| Loudspeaker | Yes |
| 3.5mm Jack | No |
| WLAN | Wi-Fi 802.11 a/b/g/n/ac, dual-band, Wi-Fi Direct |
| Bluetooth | 5.2, A2DP, LE |
| NFC | Yes (market/region dependent) |
| Radio | No |
| USB | USB Type-C 2.0, OTG |
| Sensors | Fingerprint (side-mounted), accelerometer, gyro, proximity, compass |
| Colors | Green, Blue, Brown |
| SAR EU | 0.60 W/kg (head) 1.53 W/kg (body) |