| Local Name | iQOO Neo5 S |
| Additional Information | Also known as vivo iQOO Neo5S |
| Technology | GSM / CDMA / HSPA / CDMA2000 / LTE / 5G |
| 4G Bands | 1, 3, 4, 5, 8, 28, 34, 38, 39, 40, 41 |
| 3G Bands | HSDPA 850 / 900 / 1900 / 2100 | CDMA2000 1x |
| 2G Bands | GSM 850 / 900 / 1800 / 1900 - SIM 1 & SIM 2 | CDMA 800 |
| Speed | HSPA 42.2/5.76 Mbps, LTE-A, 5G |
| Announced | 2021, December 20 |
| Status | Available. Released 2021, December 25 |
| Dimensions | 163.2 x 76.4 x 8.4 mm (6.43 x 3.01 x 0.33 in) |
| Weight | 196 g (6.91 oz) |
| SIM | Dual SIM (Nano-SIM, dual stand-by) |
| Display Type | Li-Po 4500 mAh, non-removable |
| Screen Size | 6.62 inches, 105.8 cm2 (~84.9% screen-to-body ratio) |
| Resolution | 1080 x 2400 pixels, 20:9 ratio (~398 ppi density) |
| OS | Android 11, Origin OS Ocean |
| Chipset | Qualcomm SM8350 Snapdragon 888 5G (5 nm) |
| CPU | Octa-core (1x2.84 GHz Kryo 680 & 3x2.42 GHz Kryo 680 & 4x1.80 GHz Kryo 680) |
| GPU | Adreno 660 |
| Card Slot | No |
| Internal Memory | 128GB 8GB RAM, 256GB 8GB RAM, 256GB 12GB RAM | UFS 3.1 |
| Camera Features | HDR |
| Video | 1080p@30fps |
| Loudspeaker | Yes, with stereo speakers |
| 3.5mm Jack | No |
| Sound | 24-bit/192kHz audio |
| WLAN | Wi-Fi 802.11 a/b/g/n/ac/6, dual-band, Wi-Fi Direct, hotspot |
| Bluetooth | 5.2, A2DP, LE, aptX HD, aptX Adaptive |
| GPS | Yes, with A-GPS, GLONASS, GALILEO, BDS, QZSS |
| NFC | Yes |
| Radio | No |
| USB | USB Type-C 2.0, USB On-The-Go |
| Sensors | Fingerprint (under display, optical), accelerometer, gyro, proximity, compass |
| Colors | Orange, Blue, Black |
